[CAS NO. 58-60-6] Puromycin aminonucleoside
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PRODUCTS SPECIFICATIONS [58-60-6]
Store
Catalog
SLK-S9631
Brand
Selleck
CAS
58-60-6
DESCRIPTION [58-60-6]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 294.31 |
| Molecular Formula | C12H18N6O3 |
| SMILES | O[C@H]1[C@](N2C=3C(N=C2)=C(N(C)C)N=CN3)(O[C@H](CO)[C@H]1N)[H] |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.3978 mL | 16.9889 mL | 33.9778 mL |
| 5 mM | 0.6796 mL | 3.3978 mL | 6.7956 mL |
| 10 mM | 0.3398 mL | 1.6989 mL | 3.3978 mL |
| 50 mM | 0.0680 mL | 0.3398 mL | 0.6796 mL |
Description
Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of and that induces in mesangial cells (MCs) accompanied by declined cell viability and enhanced inflammatory response.
In vitro
Puromycin aminonucleoside (PAN) induces MC apoptosis accompanied by the declined cell viability and enhanced inflammatory response. In PAN-treated MCs, ERRα overexpression further aggravates PAN-induced apoptosis.
Synonyms
Adenosine, 3′-amino-3′-deoxy-N,N-dimethyl-
3′-Amino-3′-deoxy-N,N-dimethyladenosine
SAN
Stylomycin aminonucleoside
Aminonucleoside
Puromycin, aminonucleoside
9-(3-Amino-3-deoxy-β-D-ribofuranosyl)-6-(dimethylamino)-9H-purine
6-(Dimethylamino)-9-(3-amino-3-deoxy-β-D-ribofuranosyl)purine
Aminonucleoside puromycin
3′-Amino-3′-deoxy-N6,N6-dimethyladenosine
6-Dimethylamino-9-(3-amino-3-deoxyribosyl)purine
NSC 3056
PANS
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