[CAS NO. 478188-26-0] DX600
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PRODUCTS SPECIFICATIONS [478188-26-0]
Store
Catalog
SLK-S9666
Brand
Selleck
CAS
478188-26-0
DESCRIPTION [478188-26-0]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 3074.32 |
| Molecular Formula | C141H185N35O40S2 |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 0.3253 mL | 1.6264 mL | 3.2528 mL |
| 5 mM | 0.0651 mL | 0.3253 mL | 0.6506 mL |
| 10 mM | 0.0325 mL | 0.1626 mL | 0.3253 mL |
| 50 mM | - | - | - |
Description
DX600 is a specific inhibitor of that does not cross-react with ACE.
Targets
| ACE2 [1] |
In vitro
DX600 is an ACE2 specific inhibitor that does not cross-react with ACE. Three human cell lines (Calu-3, Caco-2, Huh-7) are evaluated for the cell surface expression of ACE2 by flow cytometry and Western blot. Subsequently, whole cell lysates, cell culture supernatant, and live cells are evaluated in the assay. Calu-3 has elevated levels of ACE2 compared to Caco-2 or Huh-7. Calu-3 also demonstrates elevated ACE2 enzymatic activity in all three sources and can be inhibited by DX600.
References
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