[CAS NO. 2160546-07-4] IACS-13909
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PRODUCTS SPECIFICATIONS [2160546-07-4]
Store
Catalog
SLK-S9703
Brand
Selleck
CAS
2160546-07-4
DESCRIPTION [2160546-07-4]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 377.27 |
| Molecular Formula | C17H18Cl2N6 |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.6506 mL | 13.2531 mL | 26.5062 mL |
| 5 mM | 0.5301 mL | 2.6506 mL | 5.3012 mL |
| 10 mM | 0.2651 mL | 1.3253 mL | 2.6506 mL |
| 50 mM | 0.0530 mL | 0.2651 mL | 0.5301 mL |
Description
IACS-13909 is a specific and potent allosteric inhibitor of that suppresses signaling through the MAPK pathway.
Targets
| SHP2 [1] |
In vitro
IACS-13909 is a specific and potent allosteric inhibitor of SHP2 that suppresses signaling through the MAPK pathway. IACS-13909 potently impedes proliferation of tumors harboring a broad spectrum of activated RTKs as the oncogenic driver. IACS-13909 potently suppresses tumor cell proliferation in vitro.
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