[CAS NO. 1358715-18-0] Fluzoparib (SHR-3162)
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PRODUCTS SPECIFICATIONS [1358715-18-0]
Store
Catalog
SLK-S9712
Brand
Selleck
CAS
1358715-18-0
DESCRIPTION [1358715-18-0]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 472.40 |
| Molecular Formula | C22H16F4N6O2 |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.1169 mL | 10.5843 mL | 21.1685 mL |
| 5 mM | 0.4234 mL | 2.1169 mL | 4.2337 mL |
| 10 mM | 0.2117 mL | 1.0584 mL | 2.1169 mL |
| 50 mM | 0.0423 mL | 0.2117 mL | 0.4234 mL |
Targets
| PARP [1] |
In vitro
All four NSCLC cell lines (A549, H460, H1299, and PC9) shows decreased viability upon exposure to fluzoparib, and the effect is time and dose dependent. Fluzoparib acts synergistically to inhibit cell growth and promote apoptosis among lung cancer cells.
References
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