[CAS NO. 1399177-37-7]  TVB-2640

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PRODUCTS SPECIFICATIONS [1399177-37-7]

Store
Catalog
SLK-S9714
Brand
Selleck
CAS
1399177-37-7

DESCRIPTION [1399177-37-7]

Overview

MDL-
Molecular Weight439.55
Molecular FormulaC27H29N5O
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.2751 mL11.3753 mL22.7505 mL
5 mM0.4550 mL2.2751 mL4.5501 mL
10 mM0.2275 mL1.1375 mL2.2751 mL
50 mM0.0455 mL0.2275 mL0.4550 mL

Description

TVB-2640 (ASC-40, FASN-IN-2) is an orally bioavailable, pharmacological inhibitor with therapeutic potential in patients with NAFLD and nonalcoholic steatohepatitis.

Targets

FAS [1]

In vitro

TVB-2640 markedly inhibits SARS-CoV-2 with EC50s of 4 nM. TVB-2640 could strikingly inhibit SARS-CoV-2 new variants with similar inhibitory effects on the early-lineage SARS-CoV-2 (USA-WA1/2020) virus.