[CAS NO. 1140844-63-8] Nor-NOHA acetate
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PRODUCTS SPECIFICATIONS [1140844-63-8]
Store
Catalog
SLK-S9737
Brand
Selleck
CAS
1140844-63-8
DESCRIPTION [1140844-63-8]
Overview
| MDL | MFCD31813790 |
|---|---|
| Molecular Weight | 296.28 |
| Molecular Formula | C9H20N4O7 |
| SMILES | CC(O)=O.CC(O)=O.N[C@H](C(O)=O)CCNC(NO)=N |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.3752 mL | 16.8759 mL | 33.7519 mL |
| 5 mM | 0.6750 mL | 3.3752 mL | 6.7504 mL |
| 10 mM | 0.3375 mL | 1.6876 mL | 3.3752 mL |
| 50 mM | 0.0675 mL | 0.3375 mL | 0.6750 mL |
Description
Nor-NOHA acetate (Nω-Hydroxy-nor-L-Arginine acetate, N-OMega-hydroxy-L-norarginine acetate, N-Hydroxy-nor-L-arginine acetate) is a reversible, competitive inhibitor of . Nor-NOHA inhibits arginase activity in aorta with an IC50 of less than 1 μM, that is, similar to its effects on liver arginase (IC50 = 0.5 μM).
Targets
| liver arginase [1] (Cell-free assay) |
| 0.5 μM |
In vitro
Nor-NOHA is a very potent competitive inhibitor of rat liver arginase in vitro with the Ki of 0.5 μM.
References
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