[CAS NO. 1876467-74-1] Elimusertib (BAY-1895344)
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PRODUCTS SPECIFICATIONS [1876467-74-1]
Store
Catalog
SLK-S9864
Brand
Selleck
CAS
1876467-74-1
DESCRIPTION [1876467-74-1]
Overview
| MDL | MFCD31561442 |
|---|---|
| Molecular Weight | 375.43 |
| Molecular Formula | C20H21N7O |
| SMILES | CN1N=CC=C1C2=CC(N3[C@H](C)COCC3)=NC4=C(C5=NNC=C5)N=CC=C24 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.6636 mL | 13.3181 mL | 26.6361 mL |
| 5 mM | 0.5327 mL | 2.6636 mL | 5.3272 mL |
| 10 mM | 0.2664 mL | 1.3318 mL | 2.6636 mL |
| 50 mM | - | - | - |
Description
Elimusertib (BAY-1895344) is a very potent and highly selective inhibitor with IC50 of 7 nM. Elimusertib potently inhibits proliferation of a broad spectrum of human tumor cell lines with median IC50 of 78 nM.
Targets
| ATR [1] (Cell-free assay) |
| 7 nM |
In vitro
BAY-1895344 inhibits tumor cell growth and viability and exhibits potent antiproliferative activity in a broad spectrum of human tumor cell lines.
References
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