[CAS NO. 53995-62-3]  PFI-90

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PRODUCTS SPECIFICATIONS [53995-62-3]

Store
Catalog
SLK-S9882
Brand
Selleck
CAS
53995-62-3

DESCRIPTION [53995-62-3]

Overview

MDL-
Molecular Weight214.22
Molecular FormulaC11H10N4O
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM4.6681 mL23.3405 mL46.6810 mL
5 mM0.9336 mL4.6681 mL9.3362 mL
10 mM0.4668 mL2.3340 mL4.6681 mL
50 mM0.0934 mL0.4668 mL0.9336 mL

Description

PFI-90 is a selective inhibitor of the histone demethylase . PFI-90 induces apoptosis and cell differentiation resulting in delayed tumor progression in vivo.

Targets

KDM3B [1]

In vitro

PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. In RH4 and SCMC cells, PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased.