The library is intended to represent the "top" molecules while capturing many targets.

We added the "3 stars" chemical probes from chemicalprobes.org We also added the top ranked chemicals for targets of Pharos, with focus on Tchem

We selected 515 molecules at late stages of preclinical trials. They are named “chemical probes” inhibitors as each of them is selective against a popular target.

The promise and peril of chemical probes Nature Chemical Biology volume 11, pages 536–541 (2015) Cite this article