Epoxide-PEG-Epoxide (EPO-PEG-EPO) is a linear bifunctional crosslinking PEG reagent featuring epoxide groups at both ends of the PEG chain. The epoxide functionality undergoes anionic ring opening reactions in the presence of nucleophiles and electrophiles, allowing for versatile chemical modifications. EPO-PEG-EPO is frequently employed to crosslink or PEGylate molecules and surfaces containing amine or hydroxyl groups.
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