Folic acid PEG Fluorescein, also referred to as FITC-PEG-FA, combines the benefits of folic acid and fluorescein in a versatile compound. With its excitation/emission wavelength at 490 nm/520 nm, fluorescein imparts a bright green fluorescence to enable easy tracing of this compound. Covalently linked to the PEG chain via its terminal carboxylic groups, folic acid, also known as vitamin M, vitamin B9, or pteroyl-L-glutamic acid, contributes its essential bioactive properties. Folic acid plays pivotal roles in DNA synthesis, repair, methylation, and serves as a cofactor in various biological reactions, while also acting as a ligand to folate receptors on cell surfaces. The resulting Fluorescein PEG folic acid compound exhibits excellent solubility in aqueous solutions, facilitating its use in detecting folate receptors on cell membranes.
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