4-Arm PEG-glutamic acid (4-arm PEG-GA) is a multiarm PEG derivative featuring four terminal carboxylic acid groups linked to a pentaerythritol core. With a C3 hydrocarbon ester connecting the PEG to the glutamic acid carboxyl groups, it enables reversible PEGylation. This structure allows for effective coupling with amine groups using peptide coupling reagents like NHS, DCC, and EDC, making 4-arm PEG-GA a powerful tool for bioconjugation and targeted drug delivery applications.
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