[CAS NO. ]  4-ArmPEG-SH

• Synonyms：
  4-ArmPEG-Thiol
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

4-ArmPEG-SH is a multi-arm PEG derivative. Each end of the four arms of 4-Arm PEG-SH has a thiol group, and its reactive free sulfhydryl group can selectively react with the surface of maleimide and transition metal including gold, silver, etc.

4-ArmPEG-SH is also a reversible PEGylation and PEG hydrogel reagent. PEG-SH in 4-ArmPEG-SH can be well oxidized by air to form disulfide bonds.

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Zhang, Y., Wang, Q., Deng, W., Hazer, S., Luukkonen, A., Pranovich, A., H. Salo-Ahen, O. M., Österbacka, R., Xu, C., & Wang, X. “Grafting-to” Polymers of Xylan-g-allyl Glycidyl Ether Toughen PEG Hydrogel via Microphase Separation: Thermoresponsive and Photoreactive Molecular Assembly in DLP 3D Printing. Small, 2502129. https://doi.org/10.1002/smll.202502129
2. Chu, C.-W.; Cheng, W.-J.; Wen, B.-Y.; Liang, Y.-K.; Sheu, M.-T.; Chen, L.-C.; Lin, H.-L. Preparation and Rheological Evaluation of Thiol–Maleimide/Thiol–Thiol Double Self-Crosslinking Hyaluronic Acid-Based Hydrogels as Dermal Fillers for Aesthetic Medicine. Gels 2024, 10, 776. https://doi.org/10.3390/gels10120776 
3. Pranantyo, D., Yeo, C.K., Wu, Y. et al. Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing. Nat Commun 15, 954 (2024). https://doi.org/10.1038/s41467-024-44968-y

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