[CAS NO. ]  4-ArmPEG-SC

• Synonyms：
  4-ArmPEG-Succinimidyl ester
  4-ArmPEG-NHS
  
• Recommended Storage Condition：
  
• Uses：
  

4-ArmPEG-SC, also known as 4-Arm PEG NHS, is a reactive multi-arm PEG derivative featuring multiple succinimidyl (NHS) groups, allowing for efficient modification of proteins, peptides, and other materials via their amino groups. The NHS esters react rapidly with primary amine groups at alkaline pH to form stable amide bonds. This derivative is commonly used for hydrogel formation, nanoparticle surface modification, and various other applications. PEGylation with 4-Arm PEG NHS can significantly enhance the solubility and stability of peptides and proteins while reducing their immunogenicity. Additionally, it can suppress non-specific binding of charged molecules to modified surfaces, making it a valuable tool in biomedical and biotechnological fields.

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Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. ​Shirasu, T., Yodsanit, N., Xie, X., Zhao, Y., Wang, Y., Xie, R., Huang, Y., Wang, B., Urabe, G., Gong, S., Guo, L., & Kent, K. C. (2021). An adventitial painting modality of local drug delivery to abate intimal hyperplasia. Biomaterials, 275, 120968. https://doi.org/10.1016/j.biomaterials.2021.120968

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