8-ArmPEG-Maleimide (8-ArmPEG-MAL) is a multi-arm PEG derivative featuring maleimide groups at the termini of its eight arms, all connected to a hexaglycerol core. The maleimide groups selectively react with free thiol, SH, sulfhydryl, or mercapto groups via Michael addition, forming stable carbon-sulfur bonds. This specificity makes 8-arm PEG-MAL ideal for site-specific protein and peptide modification, enhancing the solubility, stability, and biocompatibility of the modified molecules. Its multi-functional structure allows for efficient and targeted bioconjugation, making it a valuable tool in various biomedical and biotechnological applications, including drug delivery, diagnostics, and the development of advanced biomaterials.
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