N3-PEG-NHS (Azido-PEG-NHS) is a PEG derivative functionalized with an azido group (-N3) and an N-hydroxysuccinimide (NHS) ester moiety. The NHS ester group enables the selective coupling of the Azido-PEG molecule to primary amines on biomolecules, such as proteins and peptides. The azido group further facilitates subsequent reactions via click chemistry, allowing for the attachment of various molecules or biomolecules containing alkynes or other suitable reactive groups. Azido-PEG-NHS ester is particularly valuable in the development of bioconjugates, drug delivery systems, and surface modifications due to its biocompatibility, water solubility, and versatility in facilitating controlled and specific chemical reactions.
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