[CAS NO. 564476-32-0] Br-PEG4-CH2CH2COOtBu
PRODUCTS SPECIFICATIONS [564476-32-0]
DESCRIPTION [564476-32-0]
- CAS No.：
564476-32-0 - Synonyms：
Bromo-PEG4-t-butyl ester
Br-PEG4-COOtBu
Br-PEG4-C2-Boc
15-Bromo-4,7,10,13-tetraoxapentadecanoic acid tert-butyl ester
3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-bromo-, 1,1-dimethylethylester - Purity：
≥95% - MF：
C15H29BrO6 - MW：
385.29 - Recommended Storage Condition：
Store at -5°C,keep in dry and avoid sunlight. - Uses：
Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
Br-PEG4-CH2CH2COOtBu, also known as Bromo-PEG4-t-butyl ester, is a type of PEG linker featuring a bromide group (Br) and a t-butyl protected carboxyl group (COOtBu). The bromide group acts as a leaving group in nucleophilic substitution reactions, facilitating the conjugation of the linker to biomolecules or other substrates through nucleophilic attack. The t-butyl protected carboxyl group serves as a temporary protecting group for the carboxylic acid functionality, which can be selectively removed under acidic conditions, revealing a reactive carboxyl group for further conjugation reactions.
Besides, Br-PEG4-CH2CH2COOtBu is a cleavable ADC linker with four units of PEG, making it suitable for the synthesis of ADCs.
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