[CAS NO. 1807518-72-4]  Mal-PEG1-SPA

• CAS No.：
  1807518-72-4
• Synonyms：
  Mal-PEG1-NHS ester
  Maleimide-PEG1-Succinimidyl Propionate
  
• Purity：
  ≥95%
• MF：
  C₁₃H₁₄N₂O₇
• MW：
  310.26
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Mal-PEG1-SPA (Mal-PEG1-NHS Ester) is a versatile, cleavable PEG-based linker featuring a maleimide group and an NHS ester. The maleimide group reacts specifically with thiol groups, forming stable covalent bonds, while the NHS ester efficiently conjugates with primary amines to create durable amide linkages.

The single-unit PEG spacer enhances water solubility and reduces steric hindrance, making it an ideal choice for bioconjugation applications. Widely used in the development of antibody-drug conjugates (ADCs) and PROTACs, Mal-PEG1-NHS ester is a valuable tool for precise molecular modifications in drug delivery and advanced biochemistry research.

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