[CAS NO. 156963-66-5] Benzobicyclon
PRODUCTS SPECIFICATIONS [156963-66-5]
DESCRIPTION [156963-66-5]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 446.97 |
| Molecular Formula | C22H19ClO4S2 |
| SMILES | O=C1C2CC(C(SC3=CC=CC=C3)=C1C(C4=CC=C(C=C4Cl)S(=O)(C)=O)=O)CC2 |
Summary
Benzobicyclon is a 4-HPPD inhibitor and herbicide that reacts with water to form a hydrolysate of the active herbicide benzobicycline, causing bleaching and death of weeds. Benzobicyclon is effective against grass, sedge and broadleaf weeds. Benzobicyclon effectively targets sulfonylurea herbicide-resistant biotypes as well as wild-type weeds [1] [2] .
IC50 & Target
4-HPPD [1]
In Vitro
Benzobicyclon (100-300 g a.i./ha; 1 L or 2 L) exhibits excellent herbicidal activity against
S. juncoides
regardless of the emergence depth between 0 and 3 cm and (200-300 g a.i./ha; pre-emergence; 1 L) hardly affected by the soil types
[1]
.
Benzobicyclon (300 g a.i./ha; 1-leaf and 1 L stages) completely controls
S. juncoides
at 25°C, 20°C, and 15°C, and takes longer to reach 90% control at low temperatures
[1]
.
Benzobicyclon (200, 300 g a.i./ha; pre-emergence and 1 L stages) exhibits excellent herbicidal activity against all SU-R biotypes
S. juncoides
,
M. vaginalis
and
L. dubia
as well as SU-S biotypes. (SU-S: sulfonylurea herbicide-susceptible, SU-R: sulfonylurea herbicide-resistant)
[1]
.
Benzobicyclon (200-600 g a.i./ha; pre-emergence and 1 L stages) exhibits excellent herbicidal activity against
E. crus-galli
,
S. juncoides
,
M. vaginalis
,
L. var. dubia
and
C. serotinus
and shows good rice crop safety
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay [1]
| Cell Line: | S. juncoides |
| Concentration: | 200, 300 g a.i./ha |
| Incubation Time: | pre-emergence and 1 L stages |
| Result: | Completely controlled S. juncoides in 5 types of paddy soils, namely, clay loam, loam, light clay, sandy loam, and heavy clay. |
Cell Viability Assay [1]
| Cell Line: | S. juncoides |
| Concentration: | 300 g a.i./ha |
| Incubation Time: | 1-leaf and 1 L stages |
| Result: | Showed 90% control at 25°C, 20°C, and 15°C at 14, 22, and 32 days after application, respectively. |
Cell Viability Assay [1]
| Cell Line: | S. juncoides , M. vaginalis , L. dubia |
| Concentration: | 200, 300 g a.i./ha |
| Incubation Time: | Pre-emergence and 1 L stages |
| Result: | Showed good herbicidal activity against all SU-R biotypes tested as well as SU-susceptible biotypes. |
Cell Viability Assay [1]
| Cell Line: | Transplanted rice (3 cm) |
| Concentration: | 200-600 g a.i./ha |
| Incubation Time: | Pre-emergence and 1 L stages |
| Result: | Exhibited excellent herbicidal activity and broad-herbicidal spectrum without causing injury to transplanted rice. |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 16.67 mg/mL ( 37.30 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.2373 mL | 11.1864 mL | 22.3729 mL |
| 5 mM | 0.4475 mL | 2.2373 mL | 4.4746 mL |
| 10 mM | 0.2237 mL | 1.1186 mL | 2.2373 mL |
References
- [1] Sekino K, et al. Herbicidal activity of a new paddy bleaching herbicide, benzobicyclon. Journal of Pesticide Science, 2008, 33(4): 364-370.
- [2] Williams KL, et al. Hydrolytic Activation Kinetics of the Herbicide Benzobicyclon in Simulated Aquatic Systems. J Agric Food Chem. 2016 Jun 22;64(24):4838-44.
Synonyms
