[CAS NO. 78287-27-1] 7-Ethylcamptothecin

Name: 7-Ethylcamptothecin
Brand: Arctom Scientific
SKU: HY-N2108

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [78287-27-1]

Store

Catalog

HY-N2108

Brand

MCE

CAS

78287-27-1

DESCRIPTION [78287-27-1]

Overview

MDL	MFCD06657922
Molecular Weight	376.41
Molecular Formula	C22H20N2O4
SMILES	O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC=CC=C5N=C4C3=C2)=O

For research use only. We do not sell to patients.

Summary

7-Ethylcamptothecin is one of camptothecin analogues. camptothecin (CPT), a cytotoxic alkaloid isolated from Camptotheca acuminata , is shown to have strong antitumor activity against L1210 leukemia and Walker 256 carcinosarcoma models ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 5 mg/mL ( 13.28 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6567 mL	13.2834 mL	26.5668 mL
5 mM	0.5313 mL	2.6567 mL	5.3134 mL
10 mM	0.2657 mL	1.3283 mL	2.6567 mL

* Please refer to the solubility information to select the appropriate solvent.

References

[1] Wang, X.,et al. New Route for Conversion of Camptothecin to 7-Ethylcamptothecin and 7-Propylcamptothecin. Synthetic Communications, 2007,37(3), 519–523.

Synonyms

1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4-hydroxy-, (4S)-

1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4-hydroxy-, (S)-

(4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

7-Ethylcamptothecin

SN 22

7-Ethyl-20(S)-camptothecin